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They identified these inclusions in the esophagus and colon of two PD patients with dysphagia (Qualman et al., 1984)

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The compounding-relevant chronology is also part of the public record: in February 2025 the FDA issued a declaratory order resolving the previously declared shortage of semaglutide injection products, with enforcement-discretion periods for 503A and 503B compounding concluding later that spring [8]